The NCIS: New Orleans Office is a small team that investigative cases from Pensacola through Mississippi and Louisiana to the Texas panhandle.The New Orleans Team is led by NCIS Special Agent Dwayne Cassius Pride and operates out of New Orleans, Louisiana.
- Leon Vance - Director of NCIS.
- Jerome Craig - Deputy Director of NCIS.
- Owen Granger - Assistant Director of NCIS.
- Dwayne Cassius Pride - Special Agent in Charge.
- Christopher LaSalle - Field Agent.
- Meredith Brody - Field Agent.
- Sonja Percy - Field Agent.
- Dr. Loretta Wade - Jefferson Parish Coroner.
- Wendell Hobbs - Jefferson Parish Forensic Scientist.
- Sebastian Lund- Dr. Wade's lab assistant.
- Patton Plame - A computer specialist.